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Recovery9 min read

HORMONES AND CYCLING AFTER 40: WHAT CHANGES AND WHAT TO TEST

By Anthony WalshUpdated

WHAT WE BELIEVE & WHY

  1. 01Masters athletes retain substantial aerobic capacity and muscle function compared with inactive peers, although lifelong training does not stop every age-related change.

    Roadman Position
    Do not treat every performance change after 40 as endocrine failure.
    Evidence Source
    Older-athlete nutrition and physiology review (PMID 33922108) and masters-athlete review (PMID 35122228)
    Practical Implication
  2. 02Male hypogonadism requires compatible symptoms and consistently low testosterone, not fatigue or one result alone.

    Roadman Position
    Route testosterone questions to the dedicated clinical and anti-doping owner.
    Evidence Source
    Endocrine Society testosterone guideline (DOI 10.1210/jc.2018-00229)
    Practical Implication
  3. 03The testosterone:cortisol ratio has shown group-level associations with intensified training, but evidence is inconsistent and no diagnostic threshold is established.

    Roadman Position
    Do not use the ratio to diagnose overtraining or prescribe tomorrow’s ride.
    Evidence Source
    Biomarker meta-analysis (PMID 30141022) and 2025 review (PMID 41229716)
    Practical Implication
  4. 04Thyroid testing and treatment follow clinical guidance; a cyclist-specific optimal thyroid range is not established.

    Roadman Position
    Symptoms and TSH-led assessment matter more than a full athlete thyroid panel by default.
    Evidence Source
    NICE thyroid disease guideline NG145
    Practical Implication
  5. 05Single growth-hormone measurements are not useful for diagnosing adult growth-hormone deficiency.

    Roadman Position
    A post-workout hormone spike and a clinical pituitary diagnosis are different questions.
    Evidence Source
    Endocrine Society hypopituitarism guideline
    Practical Implication
  6. 06Exercise can support health through menopause, but reviews do not justify one universal menopause-specific performance protocol.

    Roadman Position
    Adapt training to symptoms, bone health, goals and response rather than a hormone stereotype.
    Evidence Source
    Menopause exercise overview (PMID 39003439) and NHS guidance
    Practical Implication
  7. 07Resistance and impact exercise are promising for bone and function after menopause, but protocols and reporting remain heterogeneous.

    Roadman Position
    Cycling should be complemented with appropriate loading, not replaced by a rigid social-media prescription.
    Evidence Source
    Menopausal resistance and impact review (PMID 42154220)
    Practical Implication
  8. 08REDs is a multifactorial syndrome in female and male athletes and can include reproductive and endocrine effects.

    Roadman Position
    Low energy availability is assessed as a wider health and performance problem, not inferred from one hormone.
    Evidence Source
    2023 IOC REDs consensus (PMID 37752011)
    Practical Implication
  9. 09Several hormone drugs, including testosterone and growth hormone, are prohibited under current anti-doping rules.

    Roadman Position
    Medical treatment and competition permission are separate checks.
    Evidence Source
    2026 WADA Prohibited List
    Practical Implication

WHO THIS IS FOR

IS THIS YOU?

  • Cyclists over 40 trying to distinguish ordinary training fatigue from a health problem
  • Male riders with testosterone questions who need the right specialist pathway
  • Female cyclists navigating perimenopause or menopause without a one-size-fits-all training rule
  • Coaches who need a safe boundary between training context and endocrine diagnosis

THE ROADMAN VIEW

The Roadman View

  • Do not call every flat month a hormone problem. Describe the pattern, check the obvious training and fuelling causes, and escalate persistent symptoms properly.
  • A large panel is not more authoritative when the question is vague. The right test is the one that can change a qualified decision.
  • Training can improve health without “optimising” a blood hormone. Judge the programme by function, adaptation and sustainable progression.

The short answer

Hormones matter to cycling. “Hormones” do not form one system that can be scored from a panel and fixed with a training hack.

Testosterone, cortisol, thyroid hormones, growth hormone, oestrogen and progesterone have different control systems, rhythms, clinical meanings and tests. A hard ride can change several of them briefly. Age, menopause, sleep, food, medicines, illness and training history can also affect symptoms or measurements.

If recovery has slowed after 40, begin with the whole pattern:

  • What changed, and when?
  • Is cycling performance the only problem, or has daily function changed too?
  • Are there sexual, menstrual, temperature, bone, weight, mood or neurological symptoms?
  • Has training, energy intake, sleep, medication or illness changed?
  • Is there a clinical reason for a particular test?

That is a more useful starting point than “check all your hormones.”

Do hormones explain slower recovery after 40?

Sometimes. They are rarely the only explanation.

Ageing influences maximal heart rate, stroke volume, oxygen delivery, muscle mass, motor units, connective tissue, sleep and the life stress surrounding training. Masters-athlete research also shows how much capacity lifelong activity preserves compared with inactivity. A review focused on older athletes describes trainable performance and nutrition factors alongside age-related endocrine changes.

This is the useful frame: biology changes, but age does not tell you which system limits an individual rider today.

A training plateau is a prompt to investigate the programme, fuelling, recovery and health in order. It is not a blood-test diagnosis.

Testosterone: one question, not the whole panel

Testosterone influences reproductive health, bone, red-cell production, muscle and other tissues. It can change acutely with exercise, and some chronically endurance-trained men show lower resting levels.

Clinical hypogonadism still requires compatible symptoms and consistently low testosterone. Fatigue, motivation and watts are too nonspecific on their own. Total testosterone remains the first-line measurement, usually repeated on separate fasting mornings; free testosterone adds information in selected situations.

There is no validated cyclist target at the 50th–75th percentile of a free-testosterone range. There is no rule that a masters rider needs an annual testosterone panel either.

The dedicated cycling and testosterone guide covers exercise effects, symptoms, testing, significant head injury, TRT and TUE requirements. Its clinical foundation is the Endocrine Society guideline.

Cortisol: a stress hormone, not a readiness grade

Cortisol helps regulate energy, blood pressure, immune activity and the response to stress. Exercise is one of many inputs. A rise after a demanding session can be normal.

The internet often divides cortisol by testosterone and calls the result “anabolic versus catabolic balance.” Research is more cautious.

A systematic review and meta-analysis of intensified training biomarkers found some directional association between the testosterone:cortisol ratio and performance, while most biomarkers did not change consistently with performance. A later review of the ratio describes limited, conflicting data and no established threshold.

That means the ratio may be a research signal. It is not a validated diagnosis of overtraining syndrome, a personal recovery budget or a rule for placing two hard sessions.

The cycling cortisol guide explains sampling, daily rhythm and the difference between training stress and adrenal disease.

Thyroid: common symptoms, specific clinical pathway

Thyroid hormones affect metabolism and many organ systems. Hypothyroidism can cause fatigue, cold intolerance, constipation, dry skin, weight change, menstrual changes and cognitive symptoms. Those complaints overlap with underfuelling, anaemia, depression, sleep loss and training fatigue.

There is no evidence that 5–10% of endurance athletes have “subclinical hypothyroidism” or that a cyclist-specific optimal thyroid range should replace clinical interpretation.

NICE thyroid guidance uses a defined testing and treatment pathway. TSH is commonly the first test for primary thyroid disease, with free T4 and other testing used according to the result and clinical context. A default TSH, free T3 and free T4 “performance panel” is not automatically better.

The cycling thyroid guide owns this question in depth.

Does cycling increase growth hormone?

Exercise and sleep can trigger pulses of growth hormone. A temporary exercise response does not prove a higher baseline, superior adaptation or a deficiency.

Growth hormone is released in pulses, so a random measurement is particularly poor evidence. The Endocrine Society hypopituitarism guideline states that single GH measurements are not helpful and recommends stimulation testing when adult deficiency is suspected.

That pathway is for people with a clinical reason to suspect pituitary disease. It is not an annual recovery test for healthy masters athletes. IGF-1 also needs clinical context and does not become a wearable-style readiness score.

Growth hormone is prohibited under the 2026 WADA Prohibited List. It is not a masters-recovery product.

Perimenopause and menopause: symptoms vary

Perimenopause and menopause can affect menstrual bleeding, temperature regulation, sleep, mood, genitourinary health, bone and body composition. The timing and effect on training vary widely.

The evidence does not support telling every woman to use one menstrual-phase schedule, eat an identical protein dose or replace all endurance work with HIIT.

An overview of menopause exercise reviews found some symptom benefits from yoga and less consistent evidence for aerobic exercise, with insufficient evidence for one best exercise prescription. A 2026 resistance and impact review found promising interventions for bone and function but meaningful heterogeneity in design and reporting.

NHS menopause guidance recommends regular activity with weight-bearing and resistance exercise for bone health. Cycling remains valuable for aerobic fitness; it does not provide all the loading that bone needs.

Useful training decisions include:

  • adapt hard sessions when sleep or vasomotor symptoms disrupt recovery;
  • retain progressive strength work;
  • include appropriate weight-bearing or impact work where safe;
  • fuel the actual training demand;
  • investigate heavy or abnormal bleeding; and
  • discuss significant symptoms and HRT with a qualified clinician.

The menopause cycling guide covers the specialist pathway.

Low energy availability can affect multiple systems

When training demand repeatedly exceeds available dietary energy, the body can alter reproductive, bone, metabolic, immune and cardiovascular function. This can affect women and men.

The 2023 IOC REDs consensus treats REDs as a multifactorial clinical syndrome. Menstrual disruption or lower testosterone can be relevant signals, but neither one diagnoses the syndrome alone.

Look for the wider pattern:

  • deliberate restriction or unplanned weight loss;
  • recurrent bone stress or injury;
  • menstrual or sexual changes;
  • persistent fatigue or illness;
  • stalled adaptation despite rising load; and
  • anxiety or rigidity around food and body composition.

The energy-availability and REDs guide and energy-availability tool help organise the conversation. They do not replace clinical care.

Which hormone blood tests should a masters cyclist get?

There is no universal annual list.

Start with the reason for testing:

QuestionPossible clinical directionWhy a blanket panel fails
Male sexual symptoms or suggestive signsRepeat morning total testosterone; additional tests if indicatedOne free-testosterone result does not diagnose hypogonadism
Thyroid-compatible symptomsTSH-led pathway, with free T4 or other tests as indicatedAthlete “optimal” ranges are not established
Usual-age perimenopause or menopause symptomsOften a clinical diagnosis; tests depend on age and atypical featuresA single ovarian-hormone snapshot can be hard to interpret
Suspected pituitary diseaseSpecialist, axis-specific testingRandom GH and random cortisol are not screening scores
Underfuelling or REDs concernMultidisciplinary history and selected testsNo hormone result diagnoses the whole syndrome
Isolated cycling fatigueReview training, sleep, food, illness and symptoms firstMore biomarkers create more incidental results

The blood-testing owner explains how sample timing, laboratory intervals and clinical questions fit together.

What should change in training?

Do not write a programme around a hormone slogan.

Use durable principles:

  1. Keep hard days purposeful and allow enough recovery to repeat quality.
  2. Retain progressive strength training for muscle, force and bone support.
  3. Fuel high-demand sessions and avoid chronic energy deficit.
  4. Protect sleep without claiming that a particular bedtime “optimises” testosterone or growth hormone.
  5. Track menstrual, sexual, temperature, illness, bone and daily-function changes when relevant.
  6. Reassess unexplained deterioration instead of pushing through it indefinitely.

The programme can respond to symptoms before the diagnosis is known: reduce the risky load, keep gentle activity when appropriate and get the right assessment. It should not prescribe a hormone treatment.

When should a rider seek medical assessment?

Arrange assessment for persistent or worsening symptoms that affect daily function, or for more specific endocrine signs such as:

  • major menstrual change, heavy bleeding or postmenopausal bleeding;
  • reduced libido, erectile dysfunction or loss of spontaneous erections;
  • unexplained hot flushes outside the expected menopause context;
  • marked cold intolerance, bowel, skin or weight changes;
  • recurrent fractures or bone stress;
  • symptoms after significant head injury;
  • persistent severe thirst or urination; or
  • a combination of fatigue with neurological, visual or other systemic symptoms.

Seek urgent care for chest pain, fainting, severe breathlessness, acute neurological symptoms or rapid deterioration. Do not use a hard ride to test medical safety.

What the Roadman app can—and cannot—do

The app can combine:

  • symptoms and daily function;
  • training load and response;
  • sleep and illness;
  • energy availability and weight change;
  • menstrual or sexual context when the rider chooses to record it;
  • laboratory date, units, interval and sample conditions; and
  • the clinician's follow-up plan.

That creates a better timeline than scattered screenshots and isolated readiness scores.

It cannot diagnose hypogonadism, thyroid disease, adrenal disease, growth-hormone deficiency, menopause or REDs. It cannot prescribe HRT, TRT or supplements, and it cannot determine anti-doping permission.

Roadman is building a trusted context layer around training—not a hormone clinic. Join the single app waiting list for launch access.

The Roadman decision

Hormones are part of the athlete, not an explanation for every bad ride.

Use the broad overview to find the right specialist question. Test only when the result can change a qualified decision. Keep training, fuelling and recovery fundamentals strong while medical diagnosis and treatment stay with the people licensed to do them.

FAQ

FREQUENTLY ASKED QUESTIONS

Do hormones cause slower cycling recovery after 40?
They can contribute, but recovery also changes with training load, sleep, energy intake, illness, medicines, work stress, muscle damage and life context. Slower recovery alone does not identify a hormone or justify a panel. Look for a persistent pattern and clinically relevant symptoms.
Which hormone blood tests should a cyclist over 40 get annually?
There is no universal annual panel. A clinician may select testosterone, thyroid or other tests when symptoms, examination, medicines or risk make them relevant. Testing every hormone without a question increases noise and can turn normal variation into an invented performance problem.
Is the cortisol-to-testosterone ratio an overtraining test?
No validated individual threshold diagnoses overtraining or determines readiness. Research shows some directional associations during intensified training, but results are inconsistent and sampling is sensitive to time, recent exercise and other stress. Use performance, symptoms and the wider clinical picture.
Does cycling increase growth hormone?
Exercise can produce a temporary growth-hormone response, but that is not a lasting recovery score or proof of deficiency. Growth hormone is pulsatile, and Endocrine Society guidance says single measurements are not useful for diagnosing adult deficiency. Suspected pituitary disease needs specialist assessment and usually stimulation testing.
Does cycling lower testosterone after 40?
Cycling has no single inevitable effect. Some long-term high-volume male endurance athletes show lower resting testosterone, while low energy availability, illness and other causes may contribute. The dedicated guide explains symptoms, repeat testing, TRT and racing rules.
How does menopause affect cycling?
Perimenopause and menopause can affect bleeding, temperature regulation, sleep, mood, genitourinary symptoms, bone and body composition. The pattern varies substantially. Keep aerobic fitness, add appropriate strength and loading, fuel the work and seek individual menopause care when symptoms affect health or quality of life.
Should a cyclist test cortisol for fatigue?
Not as a generic readiness test. Cortisol varies with time of day, illness, food, sleep, psychological stress and exercise. Clinical testing for adrenal disease follows a specific pathway; a random value or wearable stress score cannot diagnose it.
Can low energy availability change hormones?
Yes. Inadequate energy availability can affect reproductive, bone, metabolic and other systems in women and men. One low hormone does not diagnose REDs. Review fuelling, weight change, menstrual or sexual symptoms, bone stress, illness and training with appropriately qualified care.
Can supplements balance a cyclist’s hormones?
No generic supplement stack has been shown to balance all these systems. Correct a documented nutritional deficiency when indicated, but do not use vitamin D, magnesium, zinc, DHEA, ashwagandha or “test boosters” as hormone treatment without an appropriate clinical reason.
Can the Roadman app diagnose a hormone problem?
No. It can organise symptoms, menstrual or sexual context, energy availability, sleep, training and comparable laboratory results. It cannot diagnose endocrine disease, prescribe HRT or TRT, interpret a TUE or clear a rider to train or race.

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ANTHONY WALSH

Host of the Roadman Cycling Podcast

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